Method for the production of cephalosporin C

Details Method for the production of cephalosporin C Method for the production of cephalosporin C

1976-10-28

1979-05-15

Tanenholtz, Alvin E.

Textiles: fiber preparation

C12D 904

Patent

active

041546555

ABSTRACT:
It has been discovered that a material consisting essentially of a high-ash-containing sucrose syrup, said sucrose syrup containing about 70-90% by weight solids and analyzing on a solids basis about 40-85% by weight sucrose, about 8-35% by weight invert, about 3-25% by weight ash, the remaining percent being other organic components, such as pectins, products formed by the action of heat and amino acids and alkali upon reducing sugars and up to about 10% by weight polysaccharides, is useful as a component in a medium for the growth of microorganisms. The syrup is usefully employed in a minor amount, e.g., in the range about 4-8% weight/volume in the growth medium, the syrup being added as a carbohydrate or carbon source for the growth of the microorganism. The above-described syrup is particularly useful as a component of a growth medium for the production of penicillin from a penicillin-producing microorganism and for the production of cephalosporin C by a cephalosporin C-producing microorganism.

REFERENCES:
patent: 3082155 (1963-03-01), Kelly et al.
patent: 3816257 (1974-06-01), Yamano et al.
patent: 3825473 (1974-07-01), Gargiuolo

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