Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1985-12-16
1988-12-27
Griffin, Ronald W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
210656, C08B 3702, B01D 1508, C02F 128
Patent
active
047941774
ABSTRACT:
The invention pertains to a method for the production of bead dextran materials for gel chromatography.
The subject of the invention is a method for the production of bead dextran materials for gel chromatography, wherein dextran is, before or during the suspension process or in both stages, subjected to reduction in an alkaline solution, advantageously by the action of sodium borohydride, whereas the density of crosslinking is controlled above all by variation of the concentration of the initial dextran solution and the resulting gel may be optionally subjected to the additional crosslinking in a separate subsequent operation.
The procedure according to the invention provides the product of higher quality with a lower content of carboxylic groups and substantially facilitates the preparation of gels with a very high and a very low crosslink density.
REFERENCES:
patent: 3865807 (1975-02-01), Narang et al.
patent: 4293654 (1981-10-01), Levine et al.
patent: 4446316 (1984-05-01), Chazov et al.
patent: 4474663 (1984-10-01), Nakajima et al.
patent: 4507472 (1985-03-01), Usher et al.
patent: 4591638 (1986-05-01), Ahrgren et al.
Stojanovic et al., Hemijska Industrija, vol. 33, No. 4 (1979).
Benes Milan
Coupek Jiri
Lenfeld Jiri
Peska Jan
Plichta Zedenek
Ceskoslovenska akademie ved
Griffin Ronald W.
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