Method for the production of bacterial toxins

Details Method for the production of bacterial toxins Method for the production of bacterial toxins

2005-11-29

2010-11-09

Lucas, Zachariah (Department: 1648)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S071100, C435S071300, C435S243000, C435S253600, C424S240100, C530S350000

Reexamination Certificate

active

07829321

ABSTRACT:
Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.

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