Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-05-16
2006-05-16
Navarro, Mark (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S071300, C424S184100, C424S234100, C424S236100, C424S240100
Reexamination Certificate
active
07045314
ABSTRACT:
Methods and compositions are provided for the enhanced production of bacterial toxins in large-scale cultures. Specifically, methods and compositions for reducing bacterial toxin expression inhibitors are providing including, but not limited to, addition of toxin expression inhibitor binding compounds, culture media having reduced concentrations of toxin inhibitor metabolic precursors and genetically modified toxogenic bacteria lacking enzymes required to metabolize the toxin inhibitor metabolic precursors.
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Blake Milan S.
Bogdan, Jr. John A.
Nazario-Larrieu Javier
Baxter Healthcare S.A.
Baxter International Inc.
Ford Vanessa L.
Heller Ehrman LLP
Navarro Mark
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