Method for the production of azaphenothiazines

Details Method for the production of azaphenothiazines Method for the production of azaphenothiazines

1994-03-09

1995-08-29

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 34, 546312, 546264, C07D47104, C07D40112, C07D21374

Patent

active

054461480

ABSTRACT:
6-aza-benzo[b]-phenothiazine derivatives having the formula, ##STR1## wherein X and Y can be any of hydrogen, lower alkyl, lower haloalkyl, carboxyl or carboxy alkyl are obtained through a reaction of 2-quinioline derivatives having the formula ##STR2## with a suitable 2-mercaptoaniline derivatives or dimers thereof under oxidative or free radical conditions.
The 6-aza-benzo[b]-phenothiazine derivative are valuable precursors for pharmaceutically active substances such as pipacetate, isothioperdyl and prothiperdyl.

REFERENCES:
patent: 3010961 (1928-11-01), Shindler

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