Method for the production of aminocyanoacetamide

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

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C07C25528

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active

050030990

ABSTRACT:
A large-scale industrial process for the production of aminocyanoacetamide is disclosed. A starting material is cyanoacetic acid ester, which is treated with a nitrous acid in a first step to a corresponding hydroxy-iminocyanoacetic acid ester. The hydroxy-iminocyanoacetic acid ester is then hydrogenated and, in a following step, treated with ammonia for obtaining the final product aminocyanoacetamide.

REFERENCES:
patent: 2367455 (1945-01-01), Bock et al.
Chem. Abstracts vol. 93, abst. no. 204030q (1980).
P. A. S. Smith, The Chemistry of Open-Chain Organic Nitrogen Compounds vol. 2 (W. A. Benjamin, Inc., 1966), p. 380.
Hackh's Chemical Dictionary, McGraw-Hill Book Co., 1983, pp. 26, 457.
Streitwieser, Jr. et al., Introduction to Organic Chemistry, Third Ed (1984), Macmillan Publ. pp. 253, 702.

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