Method for the production of acemetacin

Details Method for the production of acemetacin Method for the production of acemetacin

1984-10-16

1987-03-24

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548500, C07D20928

Patent

active

046526595

ABSTRACT:
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester as known per se is obtainable by a novel and more simple method comprising mild acid hydrolysis of 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetoxyacetic tetrahydropyran-2-yl ester. The final product is a valuable drug having antiinflammatory activity.

REFERENCES:
patent: 4503237 (1985-03-01), Gnehm et al.

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