Method for the production of 3-methyl cephem derivatives

Details Method for the production of 3-methyl cephem derivatives Method for the production of 3-methyl cephem derivatives

1990-08-27

1991-07-23

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540215, C07D50112

Patent

active

050345222

ABSTRACT:
A method for obtaining improved cophalexin monohydrate or cephradine monohydrate yields and purities in the syntheses of such materials by the acylation of silyl esters of 7-ADCA, which involves admixing a cephalexin or cephradine-containing system with base to separate the acid acceptor employed during acylation from the product, and thereafter separating the aqueous phase containing the cephalosporin anion from the organin phase containing the acid acceptor, to thereby prevent contamination of the desired product by the acid acceptor.

REFERENCES:
patent: Re31730 (1984-11-01), Bouzard et al.

Affiliated with

Also associated with

Rating

Method for the production of 3-methyl cephem derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the production of 3-methyl cephem derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the production of 3-methyl cephem derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-433429