Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2006-07-11
2006-07-11
Saidha, Tekchand (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S254110, C435S252300, C435S419000, C435S325000
Reexamination Certificate
active
07074608
ABSTRACT:
Recombinant organisms are provided comprising genes encoding aquacobalamin reductase, cob(II)alamin reductase, cob(I)alamin adenosyltransferase, glycerol dehydratase and 1,3-propanediol oxidoreductase activities useful for the production of 1,3-propanediol from a variety of carbon substrates. More specifically the following nucleotide sequences are provided: btuR, encoding theE. colicob(I)alamin adenosyltransferase enzyme; cobA, encoding theSalmonella typhimuriumcob(I)alamin adenosyltransferase enzyme; cobO, encoding thePseudomonas denitrificanscob(I)alamin adenosyltransferase enzyme; dhaB1, encoding the α subunit of theKlebsiellaglycerol dehydratase enzyme; dhaB2, encoding the β subunit of theKlebsiellaglycerol dehydratase enzyme; dhaB3, encoding the γ subunit of theKlebsiellaglycerol dehydratase enzyme; dhaT, encodingKlebsiellaoxidoreductase enzyme; the yciK gene isolated fromE. coli; the glucose isomerase promoter sequence fromStreptomyces; and the N-terminal amino acid sequence for cob(II)alamin reductase fromPseudomonas denitrificans.
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Dunn-Coleman Nigel S.
Gatenby Anthony A.
Valle Fernando
E. I. du Pont de Nemours and Company
Genencor International Inc.
Saidha Tekchand
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