Method for the preparation of substituted 1,4-dihydro-4-oxo-cinn

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

560 51, 560 53, 562459, 562463, 564251, C07D23728

Patent

active

051838915

ABSTRACT:
A method for the preparation of compounds of the formula ##STR1## wherein X represents a group of the formula OR.sub.1 or NR.sub.1 R.sub.2, wherein R.sub.1 and R.sub.2 independently represent H or an organic group that forms a stable covalent bond with the N or O of said X; Y is H or an organic group that forms a stable ester with the adjacent COO group; R is an alkyl or aryl group optionally substituted with one or more stable organic substituents; each R.sub.3 independently represents a stable organic group; and n is an integer from 0 to 3;

REFERENCES:
patent: 2797218 (1957-06-01), Barber et al.
patent: 3278604 (1966-10-01), Hoffman et al.
patent: 3320320 (1967-05-01), Kamlet et al.
patent: 3669965 (1972-06-01), White
patent: 3867437 (1975-02-01), Fujimura et al.
patent: 4045439 (1977-08-01), Preston et al.
patent: 4756740 (1988-07-01), Labovitz et al.
patent: 4875924 (1989-10-01), Mizutani
patent: 4956460 (1990-09-01), Fusco et al.
A. I. Meyers et al., "Oxazolines, XXII, Nucleophilic Aromatic Substitution on Aryl Oxazolines, An Efficient Approach to Unsymmetrically Substituted Biphenyls and o-Alkyl Benzoic Acids" in J. Am. Chem. Soc. (1975) 97(25):7383-7385.
Jerry March, "Reactions" in Advanced Organic Chemistry 3rd. Ed. (1985) pp. 587, published by John Wiley & Sons, New York.
Henry Feuer, "Activating Effects of the Nitro Group in Aromatic Substitutions" in The Chemistry of the Nitro and Nitroso Groups (1969) pp. 569-610, published by Interscience Publishers, New York.
A. I. Meyers et al., "Enantioselective Synthesis of Biphthyls via Nucleophilic Aromatic Substitution on Chiral Oxazolines" in J. Am. Chem. Soc. (1982) 104(3):879-881.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for the preparation of substituted 1,4-dihydro-4-oxo-cinn does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the preparation of substituted 1,4-dihydro-4-oxo-cinn, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the preparation of substituted 1,4-dihydro-4-oxo-cinn will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-7484

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.