Method for the preparation of steroid derivative ketal

Details Method for the preparation of steroid derivative ketal Method for the preparation of steroid derivative ketal

1999-01-04

1999-12-21

Dees, Jose' G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Azides

C07J 2100

Patent

active

060051248

ABSTRACT:
The invention relates to a method for the preparation of a steroid derivative ketal of formula I: ##STR1## characterized in that a compound of formula II: ##STR2## is treated with an alcohol in the presence of an orthoester, wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined by the specification.

REFERENCES:
Hoock et al., "Experimental and theoretical investigations of regioselective ketalization of estra-4,9-diene-3,17-dione." J. Prakt. Chem. vol. 337, pp. 358-362, 1995.

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