Method for the preparation of physiological effectors

Details Method for the preparation of physiological effectors Method for the preparation of physiological effectors

1984-04-30

1985-05-14

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

C12P 1300, C07F 908

Patent

active

045172978

ABSTRACT:
A method for making a biologically active 1-(0-alkyl)- or 1-(0-alkenyl)-2-acetyl-3-phosphorylcholine-sn-glycerol, useful as a pharmaceutical agent or for chemical analysis, from a 1-alkyl- (or 1-alkenyl-)-2,3-diacylglycerol.

REFERENCES:
patent: 4329302 (1982-05-01), Hanahan et al.
patent: 4382035 (1983-05-01), Eibl
Pugh et al., J. Lipid Research 18, 710-716, (1977).
Demopoulos et al., J. Biol. Chem. 254, 9355-9358, (1979).
Satouchi et al., J. Biol. Chem. 256, 4425-4432, (1981).
Heymans et al., Biochim. Biophys. Acta 666, 230-237, (1981).

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