Method for the preparation of oxazoles by condensing...

Details Method for the preparation of oxazoles by condensing... Method for the preparation of oxazoles by condensing...

2007-05-29

2009-06-09

Anderson, Rebecca L (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07544809

ABSTRACT:
The present invention is comprised of improved methods in the preparation of oxazoles which results in higher yields with less impurities and contaminants. Oxazoles constitute valuable intermediates in the synthesis of pharmaceutically active substances such as, for example peroxisome proliferator activated receptor (PPAR) agonists which are pharmaceutical actives which can have a positive influence on both lipid and glucose metabolism.

REFERENCES:
patent: 5036079 (1991-07-01), Clark et al.
patent: WO 02/16332 (2002-02-01), None
patent: WO 02/100403 (2002-12-01), None
patent: WO 2004/075815 (2004-09-01), None
patent: WO 2004/076426 (2004-09-01), None
Palmer et al. The Chemistry of Heterocyclic Compounds vol. 60: Oxazoles: Synthesis, Reactions, and Spectroscopy, Part A, 2003 John Wiley & Sons, Inc.

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