Method for the preparation of N-substituted 4-ketoproline deriva

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548533, 548537, 548538, 548540, C07D20746

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active

056313853

ABSTRACT:
Method for the preparation of N-protected 4-ketoproline derivatives of formula I ##STR1## by oxidation of the corresponding N-protected 4-hydroxyproline derivatives of ##STR2## using the system TEMPO (2,2,6,6-tetramethylpiperidinyl oxy free radical)/NaOCl.

REFERENCES:
patent: 5136101 (1992-08-01), Fried

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