Method for the preparation of microscope slides

Details Method for the preparation of microscope slides Method for the preparation of microscope slides

1995-11-14

1997-07-22

Alexander, Lyle A.

Chemistry: analytical and immunological testing

Including sample preparation

427 211, B01L 302, B01L 306

Patent

active

056503326

ABSTRACT:
An improved method and apparatus for making blood smears on microscope slides are disclosed. The method is characterized by the step of temporarily deforming the normally planar surface of a slide on which the smear is being made, rendering it slightly concave in shape. This step has been found to substantially reduce streaking and other artifacts which interfere with the formation of an uninterrupted, substantially uniform monolayer of blood cells on the slide. Preferably, the movement of a blood-smearing member across the slide is controlled as a function of various predetermined physical parameters of the blood.

REFERENCES:
patent: 3146163 (1964-08-01), Brewer
patent: 3495926 (1970-02-01), Naz
patent: 3985096 (1976-10-01), Guimbretiere
patent: 3995022 (1976-11-01), Heanley et al.
patent: 4061108 (1977-12-01), Levine et al.
patent: 4378333 (1983-03-01), Laipply
patent: 4687529 (1987-08-01), Wang
patent: 5209903 (1993-05-01), Kanamori et al.

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