Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1983-09-13
1984-05-15
Schain, Howard E.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
106155, 106157, 1283355, 128DIG8, C07G 700, C08H 100, C08H 106
Patent
active
044487185
ABSTRACT:
A process for preparing a crosslinked collagen-glycosaminoglycan composite material which comprises forming an uncrosslinked composite material from collagen and a glycosaminoglycan and contacting the uncrosslinked composite with a gaseous aldehyde until a crosslinked product having an M.sub.c of from about 800 to about 60,000 is disclosed along with composite materials prepared by this process. Artificial skin produced by this process is more stable toward long-term storage than similar materials prepared using other methods of crosslinking.
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Ruderman et al., J. Biomed. Mater. Res. 7, 263-265, (1973).
Kirk James F.
Yannas Ioannis V.
Engellenner Thomas J.
Massachusetts Institute of Technology
Neeley Richard
Schain Howard E.
Smith, Jr. Arthur A.
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