Method for the preparation of arylalkanolamineacylates

Details Method for the preparation of arylalkanolamineacylates Method for the preparation of arylalkanolamineacylates

1994-04-29

1995-02-28

Henley, III, Raymond

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

562490, 562577, 562606, 562503, 562498, 562504, 562505, 562506, 562508, C07C23100

Patent

active

053939247

ABSTRACT:
Acylamides or amine acylate salts of arylalkanolamines are prepared by reacting an arylisonitrosoalkanone with hydrogen and a carboxylic acid, carboxylic acid anhydride or carboxylic acid ester or mixture thereof in the presence of a transition metal catalyst; optionally the product is converted to the corresponding arylalkanolamine hydrochloride salt by reaction of the acylamide or amine acylate salt of the arylalkanolamine with hydrogen chloride in a C.sub.1 -C.sub.3 alkyl alcohol.

REFERENCES:
patent: 1995709 (1931-09-01), Hartung et al.
patent: 2567906 (1951-09-01), Hartung et al.
patent: 3966813 (1976-06-01), Satzinger et al.
patent: 5338884 (1994-08-01), Tafesh et al.

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