Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1991-09-17
1993-08-24
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435227, 435280, 435123, C12P 740, C12P 1702, C12P 764, C12N 978
Patent
active
052388280
ABSTRACT:
An efficient microbiological or biochemical method is proposed for the preparation of an optically active 2-substituted carboxylic acid, e.g., 2-chloropropionic acid, 2-methyl butyric acid and the like, from the corresponding 2-substituted nitrile compound, e.g., 2-chloropropionitrile, 2-methyl butyronitrile and the like, in the form of a racemic body as the starting material The method comprises bringing the starting nitrile compound into contact with a microorganism, such as Pseudomonas sp. MY-1 (FERM BP-2541), Fusarium sp. MY-2 (FERM BP-2542) and the like, capable of converting the nitrile compound into the carboxylic acid in a buffered aqueous medium in which the microbial cells of the microorganism are suspended.
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Goodfellow et al. "Biology of the Actiuowycetes", Academiclress, 1984, pp. 44-46.
Idemitsu Kosan Company Limited
Marx Irene
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