Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1986-11-10
1988-11-08
Warren, Charles F.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435135, 435244, 435911, 435254, C12P 764
Patent
active
047834080
ABSTRACT:
A very efficient microbiological method is proposed for the preparation of .gamma.-linolenic acid or a lipid rich in the content of .gamma.-linolenic acid, one of the essential fatty acids in the diet of mammals, e.g. human. The method comprises culturing a fungus of Mortierella genus including isabellina, vinacea, ramanniana, ramanniana var. angulispora and nana in a culture medium containing a carbohydrate, e.g. glucose, as the carbon source in an unusually high concentration of 60 to 400 g/liter to grow a fungal body containing a large amount of a lipid rich in the content of .gamma.-linolenic acid. A further improvement in the efficiency of culture and the content of the desired fatty acid in the fungal body is obtained by the addition of acetic acid or an alkali acetate to the culture medium.
REFERENCES:
Journal of General Microbiology, (1965), 41, 127-134, Nutritional Factors in Relation to Growth and Fat Synthesis in Mortierella Vinacea,Chesters C.G.C.
Chem. Abs., vol. 98, p. 537, #33069f, Lipid High in --Linolenic Acid.
Suzuki Osamu
Yokochi Toshihiro
Director-General of the Agency of Industrial Science & Technolog
Marx Irene
Warren Charles F.
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