Method for the preparation of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

Reexamination Certificate

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C512S022000

Reexamination Certificate

active

07019181

ABSTRACT:
A method is described for the preparation of a trimethylcyclohexyl-alkan-3-ol containing a proportion of trans isomer of Formula DwhereR=H, Me, Et, n-propyl, iso-propyl, n-butyl, iso-butyl or tert-butyl andR1=Me, Et, n-propyl, iso-propyl, n-butyl, iso-butyl or tert-butyl,or of a mixture of several such trimethylcyclohexyl-alkan-3-ols,wherein the method comprises catalytically hydrogenating corresponding compound(s) of Formula Bin which R and R1 in each case have the indicated meanings, in the presence of a nickel catalyst, preferably of Raney nickel, and in an absence of catalytically active amounts of copper chromite.

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Chemical Abstracts Service, Gvinter, L.I. et al., Changes in the Selectivity of Catalytic Action During Hydrogenation of the Dienone Group. IX. Hydrogenation of ?-ionone on Nickel Catalysts, XP002258888, Abstract 83843517 (1975).
Sovoia D et al., Active Metals from Potassium-Graphite. Air-Oxidized Nickel-Graphite as a New Selective Hydrogenation Catalyst, Journal of Organic Chemistry, vol. 46, (1981), pp. 5344-5348, XP009016115.

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