Method for the preparation of 3-amino-2-chloro-4-alkylpyridines

Details Method for the preparation of 3-amino-2-chloro-4-alkylpyridines Method for the preparation of 3-amino-2-chloro-4-alkylpyridines

1995-06-07

1997-08-05

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5462701, 546289, 546295, 546304, 546307, 546309, 546310, C07F 958, C07D40904, C07D21381, C07D21334

Patent

active

056544294

ABSTRACT:
A process for the preparation of a 3-amino-2-chloro-4-alkylpyridine of the formula: ##STR1## wherein R1 is a linear, branched or cyclic hydrocarbon of from one to eight carbon atoms, optionally substituted with one or more electron stabilizing groups,
an intermediate in the preparation of certain 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine compounds useful in the prevention and treatment of HIV infection.

REFERENCES:
patent: 4172095 (1979-10-01), Steinman et al.
patent: 4209464 (1980-06-01), Steinman et al.
patent: 4404069 (1983-09-01), Goodin et al.
patent: 4480130 (1984-10-01), Ku et al.
patent: 4493755 (1985-01-01), Goodin et al.
patent: 4496765 (1985-01-01), Ku et al.
patent: 5200522 (1993-04-01), Grozinger et al.
P. Claus, W. Vycudlilik and W. Rieder "Die basenkatalysierte Umlagerung von N-Aryl-S,S-dialkylsulfimiden zu o-Alkylthiolkylanilinen", Monatsheft for Chemie, 102, pp. 1571-1582 (1971).
P. Clause and W. Rider, "Zum Mechanismus der Umlagerung von N-Aryl-S,S-dimethylsufimiden zu o-Methylthiomethylanilnen"Manatshefte fur Chemie, 103, pp. 1163-1177 (1972).
P. Gassman and D. Amick, "Exclusive Ortho Substitution of Phenols via [2,3]-Sigmatropic Rearrangements", J. Med. Chem. Soc., 100, pp. 7611-7619, (1978).

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