Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1982-01-05
1984-08-28
Hazel, Blondel
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 23, 536 29, 424 89, A61K 3170, A61K 39245
Patent
active
044683847
ABSTRACT:
A method for inhibiting the replication of a DNA virus which induces formation of thymidine kinase enzyme, by exposing the virus to an effective concentration of a compound of the formula: ##STR1## wherein R.sub.1 is a radical selected from the group consisting of halogen, --SCH.sub.3, --OH, alkoxy, cyano, methylamino, carboxy, formyl, nitro and unsubstituted or halosubstituted hydrocarbon groups of 1 through 3 carbon atoms; R.sub.2 is hydrogen; halogen or hydroxy; and R.sub.3 is hydroxy, --OP(O)(OH).sub.2, amino, or --OOR.sub.4 where R.sub.4 is lower alkyl of 1 through 6 carbon atoms.
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Bardos Thomas J.
Cheng Yung-Chi
Schroeder Alan C.
Dunn Michael L.
Ellis Howard M.
Hazel Blondel
The Research Foundation of State University of New York
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