Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-04-13
1997-03-25
Ziska, Suzanne E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351723, 424 9321, C12N 1500, C12N 500, C12D 2106, A01N 6300
Patent
active
056143818
ABSTRACT:
In the production of proteins of biological interest by means of a stress inducible gene expression unit/eukaryotic host cell system, the transformed cell lines are multiplicated by tumour growing in immunodefficient warm-blooded animals, after which the multiplicated cells are cultured in vitro and subjected to stress, whereby expression occurs in high yield. In vivo multiplication rates of 10.sup.5 -10.sup.6 the innoculated quantity/2 weeks are reported without any loss of the latent inducible expression capacity.
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Bromley Peter
Dreano Michel
Fischbach Michel
Fouillet Xavier
Padieu Prudent
Rothwell Properties Limited
Ziska Suzanne E.
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