Method for the immunological determination of the carboxytermina

Details Method for the immunological determination of the carboxytermina Method for the immunological determination of the carboxytermina

1995-06-05

1997-12-16

Housel, James C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 792, 435 793, 435 794, 435971, 435975, 436536, 436538, 436540, 436804, 436805, 436808, 5303871, 5303881, 5303891, 5303911, 5303913, G01N 3353

Patent

active

056984073

ABSTRACT:
A carboxyterminal propeptide of type I procollagen free from type III procollagen carboxyterminal propeptide can be used to produce an antibody which is specific for carboxyterminal propeptide of type I procollagen and which has no affinity for the type III procollagen carboxyterminal propeptide. This antibody can be used to assay more accurately the propeptide which is a measure of the rate of production of type I procollagen and useful in diagnosing and monitoring e.g. bone diseases.

REFERENCES:
Taubman et al., "Radioimmunoassay of Procollagen in Serum of Patients with Paget's Disease of Bone", Proc. Soc. Exp. Biol. Med., vol. 152, pp. 284-287 (1976).
Melkko et al., "Radioimmunoassay of the Carboxy Terminal Propeptide of Human Type I Procollagen", Clin. Chem., vol. 36, No. 7, pp. 1328-1332, (1990).
Simon et al., J. Clin. Endocrin Metab., vol. 58, No. 1, pp. 110-120, (1984).
McDonald et al., J. Clin. Invest., vol. 78, pp. 1237-1244, (1986).
Malizia, et al., The Lancetti, pp. 1055-1057, (1987).
Oellerich, J. Clin Chem Clin Biochem, vol. 22, pp. 895-904, (1984).
B.R. Olsen et al, Biochemistry, vol. 16, No. 13, Jun. 28, 1977, pp. 3030-3036.
K.P. Mintz et al, Chemical Abstracts, vol. 113, No. 17, Oct. 22, 1990 p. 379, Abs. No. 148293v, Columbus, Ohio, U.S.
M. Katayama et al, Chemical Abstracts, vol. 113, No. 17, Oct. 22, 1990 p. 378, Abs. No. 148282a, Columbus, Ohio, U.S.
Y. Niitsu et al, Chemical Abstracts, vol. 109, No. 17, Oct. 24, 1988 p. 522, Abs. No. 147210w, Columbus, Ohio, U.S.
B.H. Davis et al, Chemical Abstracts, vol. 106, No. 19, May 11, 1987 p. 349, Abs. No. 152462x, Columbus, Ohio, U.S.
J.A. McDonald et al, Chemical Abstracts, vol. 105, No. 25, Dec. 22, 1986, Abs. No. 223803b, Columbus, Ohio, U.S.
E. Kessler et al, Biological Abstracts, vol. 89, No. 5, 1990, p. 553, Abs. No. 45366, Philadelphia, PA, U.S.
G. Malizia et al, Biological Abstracts, vol. 85, No. 4, 1988 p. 349, Abs. No. 35511, Philadelphia, PA, U.S.
L. Risteli, Scand J Clin Invest, vol. 50, Supplement 202, 1990, pp. 143-146.
J. Melkko et al, Clinical Chemistry vol. 36, No. 7, Jul. 1990, pp. 1328-1332, Washington, D.C., U.S.
Goldberg et al., "The Carboxyl Fragment Released by Bacterial Collagenase From Human Type I Procollagen: Antibodies to the Peptide Determinants", Collagen Rel. Res., vol. 5, 1985, pp. 393-404.
Risteli et al., "The Carboxyterminal Propeptide of Procollagen Type I (PICP) In Serum and Biological Fluids", Abstract of paper given at the XXII Nordic Congress of Clinical Chemistry (Jun. 25 to 28, 1990).

Affiliated with

Also associated with

Rating

Method for the immunological determination of the carboxytermina does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the immunological determination of the carboxytermina, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the immunological determination of the carboxytermina will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-204719