Method for the identification of molecules and biomarkers...

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical

Reexamination Certificate

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C702S022000, C702S023000, C702S027000, C702S028000, C702S030000, C702S032000, C702S076000

Reexamination Certificate

active

07373256

ABSTRACT:
This invention pertains generally to the field of multivariate statistics, and in particular to new methods for the analysis (e.g., chemometrics) of chemical, biochemical, and biological data, including, for example, spectral data, including but not limited to nuclear magnetic resonance (NMR) spectral data. These methods are useful, for example, in metabonomics, proteomics, transcriptomics, genomics, etc., and form a part of other methods, for example, methods for the identification of chemical species, methods for the identification of biomarkers that are useful in methods of classification, diagnosis, prognosis, etc.

REFERENCES:
patent: 4800279 (1989-01-01), Hieftje et al.
patent: 5121337 (1992-06-01), Brown
patent: 5446681 (1995-08-01), Gethner et al.
patent: 5712797 (1998-01-01), Descales et al.
patent: 5850623 (1998-12-01), Carman et al.
patent: 6070128 (2000-05-01), Descales et al.
patent: 7181348 (2007-02-01), Wishart et al.
patent: 7191069 (2007-03-01), Wishart et al.
patent: 2002/0145425 (2002-10-01), Ebbels et al.
patent: 2003/0129666 (2003-07-01), Tanaka et al.
patent: 2007/0023627 (2007-02-01), Finch et al.
patent: 2007/0061091 (2007-03-01), Schweitzer et al.
Beebe, K.B. et al, 1998,Chemometrics: A Practical Guide, John Wiley & Sons: New York, pp. 56-182.
Braunschweiler, L., et al, 1983, “Coherence transfer by istropic mixing: application to proton correlation spectroscopy”,Magn. Reson., vol. 53, pp. 521-528.
Brindle, J.T. et al, 2002, “Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using1H-NMR-based metabonomics”,Nat. Med., vol. 8, pp. 1439-1444.
Claridge, T.D.W., 1999,High-Resolution NMR techniques in Organic Chemistry; Elsevier: Amsterdam.
Cloarec, O., et al, 2005, “Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in1H NMR spectroscopic metabonomic studies”,Anal. Chem., vol. 77, pp. 517-526.
Cloarec, O., et al., 2005, “Statistical total correlation spectroscopy: An exploratory approach for latent biomarker identification from metabolic1H NMR data sets”,Anal. Chem., vol. 77, pp. 1282-1289.
Holmes, E., et al, 1994, “Automatic data reduction and pattern recognition methods for analysis of1H nuclear magnetic resonance spectra of human urine from normal and pathological states”,Anal. Biochem., vol. 220, pp. 284-296.
Holmes, E., et al, 2000, “Chemometric models for toxicity classification based on NMR spectra of biofluids”,Chem. Res. Toxicol., vol. 13, pp. 471-478.
Holmes, E., et al, 1998, “The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine”,Chemom. Intell. Lab. Syst., vol. 44, pp. 245-255.
Lindon, J. C., et al, 2003, “So what's the deal with tabonomics? Metabonomics measures the fingerprint of biochemical perturbations caused by disease, drugs, and toxins”,Anal. Chem., vol. 75, pp. 385A-391A.
Nicholson, J. K., et al, 1999, “Metabonomics'; understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data”,Xenobiotica, vol. 29, pp. 1181-1189.
Noda, I., 1989, “Two-dimensional infrared spectroscopy”,J. Am. Chem. Soc., vol. 111, pp. 8116-8118.
Noda, I., 1993, “Generalized two-dimensional correlation method applicable to infrared, raman, and other types of spectroscopy”,Appl. Spectrosc., vol. 47, pp. 1329-1336.
Noda, I., 1990, “Two-dimensional infrared (2D IR) spectroscopy: theory and applications”,Appl. Spectrosc., vol. 44, pp. 550-561.
Noda, I., et al, 2000, “Generalized two-dimensional correlation spectroscopy”,Appl. Spectrosc., vol. 54, pp. 236A-248A.
Osaki, Y., et al, 1998, “Two-dimensional near infrared correlation spectroscopy: principle and its applications”,J. Near Infrared Spectrosc., vol. 6, pp. 19-31.
Plumb, R. S., et al, 2002, “Metabonomics: the use of electrospray mass spectrometry coupled to reversed-phase liquid chromatography shows potential for the screening of rat urine in drug development”,Rapid Commun. Mass Spectrom., vol. 16, pp. 1991-1996.
Sasic, S., et al, 2000, “A new possibility of the generalized two-dimensional correlation spectroscopy. 1. Sample—sample correlation spectroscopy”,J. Phys. Chem. A, vol. 104, pp. 6380-6387.
Trygg, J., et al, 2002, “Orthogonal projections to latent structures (O-PLS)”,J. Chemom., vol. 16, pp. 119-128.
Trygg, J., 2002, “O2-PLS for qualitative and quantitative analysis in multivariate calibration”,J. Chemom., vol. 16, pp. 283-293.
Trygg, J., et al, 2003, “O2-PLS, a two-block (X-Y) latent variable regression (LVR) method with an integral OSC filter”,J. Chemom., vol. 17, pp. 53-64.

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