Method for the fluorescent labelling of sugars

Details Method for the fluorescent labelling of sugars Method for the fluorescent labelling of sugars

1988-06-22

1990-12-04

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 11, 536124, 436546, C07H 100, C07H 506, C07H 1702

Patent

active

049755331

ABSTRACT:
A method for the fluorescent labelling of a sugar or a sugar chain by labelling the reducing end of the sugar or sugar chain with a fluorescent substance, wherein the improvement comprises first forming a Schiff base by reacting the surgar or sugar chain with the fluorescent substance in the presence of an acid which is substantially free from water, and second, reducing said Schiff base.

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patent: 4801504 (1989-01-01), Burdick et al.
Her et al., J. Carbohydrate Chemistry, 6(1), 1987, pp. 129-139.
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Hase et al., J. Biochem. 95:197-203 (1984).
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Tang et al., Carb. Res 136:259-271 (1985).
Coles et al., Carb. Res. 139:1-11 (1985).
Hase et al., J. Biochem. 90:1275-1279 (1981).

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