Method for the diagnosis of Legionnaires' disease

Details Method for the diagnosis of Legionnaires' disease Method for the diagnosis of Legionnaires' disease

1981-09-21

1985-04-30

Nucker, Christine M.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

436531, 436545, 436547, 436804, 436811, 435 7, 435 29, 435 34, 435 35, G01N 3356, C12Q 120

Patent

active

045145091

ABSTRACT:
A rapid, sensitive, and specific method for diagnosing Legionnaires' disease through the detection of antigens excreted by the patient and a method for preparing anti-Legionella immunoglobulin G for use in such diagnostic method.

REFERENCES:
Farshy et al., Detection of Antibodies to Legionnaire's Disease Organism by Microagglutination and Micro-Enzyme-Linked Immunosorbent Assay Tests, J. Clin. Microbiol., vol. 7, 327 (1978).
Kohler et al., Rapid Diagnosis of Pseudomonas Urinary Tract Infections by Radioimmunoassay, J. Clin. Microbiol., vol. 9, 253-254 (1979).
Tregear et al., Solid Phase Radioimmunoassay in Antibody Coated Tubes, Science 158:1570-1571 (1967).
Baumann et al., Solid Phase Radioimmunoassay for Human Growth Hormone, Immunochemistry 6:699-713 (1969).
Ling et al., Prevalence of Hepatitis B Virus Antigen as Revealed by Direct Radioimmune Assay with 125I-Antibody, J. Immunol. 109:834-841 (1972).
Berdal et al., Detection of Legionella pneumophila Antigen in Urine by Enzyme-Linked Immunospecific Assay, J. Clin, Microbiol, vol. 9, 575-576 (1979).
Tilton, Legionnaire's Disease Antigen Detected by Enzyme-Linked Immunosorbent Assay, Ann. Int. Med., vol. 90, 697-698 (1979).
Chard, Radioimmunoassay and Related Techniques, North-Holland Pub. Co., Amsterdam, 1978, p. 303.
Mangiafico et al., J. Clin. Microbiol., 13(5):843-845 (1981).
Johnson et al., Chemical Abstracts, vol. 91 (1979) #3720Z.

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