Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2008-03-18
2010-06-08
Horlick, Kenneth R. (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
Reexamination Certificate
active
07732143
ABSTRACT:
The invention concerns a method for detecting or locating one or several genes of one or several specific A DNA sequence or one or several molecules reacting with DNA on a B DNA characterised in that it consists in: (a) fixing and combing a certain amount of said B DNA on a combing surface; (b) reacting the product of the B combing with one or several probes, linked with the gene(s) or specific A DNA sequences, or with the molecules capable of reacting with DNA; (c) extracting information corresponding to at least one of the following categories: (1) the position of the probes, (2) the distance between the probes, (3) the size of the probes (the total sum of sizes for quantifying the number of hybridised probes) for determining therefrom the presence, the location and/or the amount of genes or specific A DNA sequences. This method can be used in particular for the diagnosis of genetic diseases.
REFERENCES:
patent: 5079169 (1992-01-01), Chu et al.
patent: 5356776 (1994-10-01), Kambara et al.
patent: 5660988 (1997-08-01), Duck et al.
patent: 5677126 (1997-10-01), Bensimon et al.
patent: 5707797 (1998-01-01), Windle
patent: 5840862 (1998-11-01), Bensimon et al.
patent: 5846724 (1998-12-01), Bensimon et al.
patent: 5851769 (1998-12-01), Gray et al.
patent: 6054327 (2000-04-01), Bensimon et al.
patent: 6265153 (2001-07-01), Bensimon et al.
patent: 6294324 (2001-09-01), Bensimon et al.
patent: 6303296 (2001-10-01), Bensimon et al.
patent: 6548255 (2003-04-01), Bensimon et al.
patent: 7368234 (2008-05-01), Bensimon et al.
patent: 2003/0175779 (2003-09-01), Bensimon et al.
patent: WO 93/18186 (1993-09-01), None
patent: WO 95/09929 (1995-04-01), None
patent: WO 95/21939 (1995-08-01), None
patent: WO 96/17958 (1996-06-01), None
patent: WO 97/18326 (1997-05-01), None
Bensimon et al., “Alignment and Sensitive Detection of DNA by a Moving Interface”,Science265:2096-2098 (Sep. 30, 1994).
Desmaze et al., “In Situ Hybridization of Fluorescent Probes on Chromosomes, Nuclei or Stretched DNA: Applications in Physical Mapping and Characterization of Genomic Rearrangements”,Cellular and Molecular Biology41(7):925-931 (1995).
Du Manoir et al., “Detection of Complete and Partial Chromosome Gains and Losses by Comparative Genomic In Situ Hybridization ”,Hum. Genet.90:590-610 (1993).
Du Manoir et al., “Quantitative Analysis of Comparative Genomic Hybridization”,Cytometry19:27-41 (1995).
International Search Report for PCT/FR97/01949 (with English version).
Kallioniemi et al., “Comparative Genomic Hybridization for Molecular Cytogenic Analysis of Solid Tumors,”Science258: 818-821 (Oct. 30, 1992).
Lebofsky et al., “Single DNA Molecule Analysis: Applications of Molecular Combing”,Briefings in Functional Genomics and Proteomics, 1(4):385-396 (2003).
Lichter et al., “High-Resolution Mapping of Human Chromosomes 11 by In Situ Hybridization With Cosmid Clones”,Science247:64-69 (1990).
Michalet et al., “Dynamic Molecular Combing: Stretching the Whole Human Genome for High-Resolution Studies”Science277:1518-1523 (Sep. 1997).
Parra et al., “High Resolution Visual Mapping of Stretched DNA by Fluorescent Hybridization”Nature Genetics5:17-21 (1993).
Piper et al., “Computer Image Analysis of Comparative Genomic Hybridization”,Cytometry19:10-26 (1995).
Bensimon Aaron
Bensimon David
Michalet Xavier
Centre National de la Recherche Scientifique "CNRS"
Finnegan Henderson Farabow Garrett & Dunner LLP
Horlick Kenneth R.
Institut Pasteur
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