Method for the diagnosis of depression based on monitoring blood

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 792, 435961, 435975, 436174, 436518, 436524, 436528, 436811, G01N 3353

Patent

active

055915884

ABSTRACT:
The invention provides a novel means of diagnosing, or confirming a diagnosis of, affective disorders, such as depression, based on the blood levels of arginine vasopressin and thymopoietin, either alone or in combination.

REFERENCES:
patent: 4124700 (1978-11-01), Goldstein
E. Zimmerman, "Oxytocin, Vasopressin, and Neurophysin", Brain Peptides, D. Kreiger et al, eds. John Wiley & Sons, New York, Ch. 25, pp. 598-611 (Oct. 31, 1983).
D. deGoeij et al, "Chronic Phychological Stress Enhances Vasopressin, but not Corticotropin-Releasing Factor, in the External Zone of the Median Eminence of Male Rats: Relationship to Suborinate Status", Endocrinol., 131 (2);847-853 (1992).
F. Antoni, "Vasopressinergic Control of Pituitary Adrenocorticotropin Secretion Comes of Age", Frontiers in Neuroendocrinol., 14(2):76-122 (Mar. 1993).
M. Hammer, "Radioimmunoassay of 8-Arginine-Vasopressin (Antidiuretic Hormone) in Human Plasma", Scand. J. Clin. Lab. Invest., 38:707-716 (1978).
P. Soelberg Sorensen et al, "Cerebrospinal Fluid Vasopressin in Neurological and Psychiatric Disorders", J. Neurol. Neurosurg. and Phsych., 48:50-57 (Jan. 1985).
A. Gjerris, "Do Concentrations of Neurotransmitters in Lumbar CSF Reflect Cerebral Dysfunction in Depression?", Acta Psychiatr. Scand., 78(345):21-24 (1988).
A. Gjerris et al, "Cerebrospinal Fluid Vasopressin --Changes in Depression", British J. Phsychiat., 147:696-701 (Dec. 1985).
P. Gold et al, "Neurohypophyseal Function in Affective Illness", Psychopharmacol. Bull., 19(3):426-431 (1983).
S. Hou, "Syndrome of Inappropriate Antidiuretic Hormone Secretion", The Neurohypophysis, Ch. 9, pp. 165-189, S. Reichlin, ed., Plenum Press, New York (May 1984).
Textbook of Endocrinology, 7th ed., Wilson & Foster, eds., pp. 644-645 (1985).
G. Sunshine et al, "Thymopoietin Enhances the Allogeneic Response and Cyclic GMP Levels of Mouse Peripheral, Thymus-Derived Lympohocytes", J. Immunol., 120:1594-1599 (May 1978).
G. Goldstein, "Isolation of Bovine Thymin: a Polypeptide Hormone of the Thymus", Nature, 247:11-14 (Jan. 1974).
D. Schlesinger and G. Goldstein, "The Amino Acid Sequence of Thymopoietin II", Cell, 5:361-365 (Aug. 1975).
G. Goldstein et al, "Thymopoietin and Myasthenia Gravis: Neostigmine-Responsive Neuromuscular Block Produced in Mice by a Synthetic Peptide Fragment of Thymopoietin", Lancet, 2:256-262 (Aug. 1975).
R. Brown et al, "Immunoreactive Thymopoietin in the Mouse Central Nervous System", Brain Research, 381:237-243 (Aug. 1986).
J. Twomey et al, "Bioassay Determinations of Thymopoietin and Thymic Hormone Levels in Human Plasma", Proc. Natl. Acad. Sci. USA, 74:2541-2545 (Jun. 1977).
V. Lewis et al, "Age, Thymic Involution, and Circulating Thymic Hormone Activity", J. Clin. Endo. Metab., 47(1):145-150 (Jul. 1978).
J. Twomey et al, "An Inhibitor of Thymic Hormone Activity in Serum from Patients with Lymphoblastic Leukemia", Am. J. Med., 68:377-380 (Mar. 1980).
G. Goldstein, "Radioimmunoassay for Thymopoietin", J. Immunol., 117:690-692 (Aug. 1976).
P. Lisi et al, "Improved Radioimmunoassay Technique for Measuring Serum Thymopoietin", Clin. Chim. ACTA, 107:111-119 (Oct. 1980).
A. Fuccello et al, "Immunoassay for Bovine Serum Thymopoietin: Discrimination from Splenin by Monoclonal Antibodies", Arch. Biochem. Biophys., 228:292-298 (Jan. 1984).
G. Goldstein and I. Mackay, "The Thymus and Experimental Pathology", The Human Thymus, Wm. Heineman Med. Books Ltd., London (1969).
G. Goldstein, "Thymitis and Myasthenia Gravis", Lancet, 2:1164-1167 (Nov. 1966).
P. Gold et al, "Vasopressin Function in Depression and Mania", Psychopharmacol. Bull., 17(1):7-9 (Jan. 1981).
P. Gold et al, "Central Peptide Function in Affective Illness: Arginine Vasopressin as a Model System", Adv. Biol. Psychiat., 7:42-70 (1981).
Hammer M., Scand J. Clin. Lab. Invest. 38:707-716 (1978).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for the diagnosis of depression based on monitoring blood does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the diagnosis of depression based on monitoring blood, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the diagnosis of depression based on monitoring blood will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1763155

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.