Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1993-07-23
1996-06-18
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
4352401, 4352402, 43524023, 435974, 530325, 530326, C12Q 170
Patent
active
055276660
ABSTRACT:
A method for the diagnosis in vitro of HIV-1 infections by treating CD4-positive cells infected with blood and other biological materials with synthetic peptides derived from V3 region of HTLV-III B strain and from MN strain of HIV-1 virus is reported. The above peptides enhance the infectivity of HIV-1 virus in cellular cultures in vitro.
REFERENCES:
patent: 5017688 (1991-05-01), Gilbert et al.
Matsushita et al, "Characterization of a HIV Neutralizing Monoclonal Antibody & Mapping of the Neutralizing Epitope" J. Virol vol. 62, No. 6 pp. 2107-2114 (1988).
Devash et al, "C-Terminal Fragments of gp120 & Synthetic Peptides from 5 HTLV-III Strains: Prevalence of Antibodies to the HTLV-III-MN Isotate in Infected Individuals." AIDS Res & Hum Retrov vol. 6, No. 3 pp. 307-316 (1990).
Autiero et al., Journal of Virology, 185, pp. 820-828 (1991).
Rusche et al., Proc. Nat'l. Acad. Sci., vol. 85, pp. 3198-3202 (1988).
Chieco-Bianchi Luigi
De Rossi Anita
Dettin Monica
Di Bello Carlo
Mammano Fabrizio
Consiglio Nazionale Delle Ricerche
Istituto Superiore Di Sanita
Nucker Christine M.
Stucker Jeffrey
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