Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2006-11-23
2011-12-06
Kapushoc, Stephen (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C536S023100, C536S024300
Reexamination Certificate
active
08071297
ABSTRACT:
The present invention refers to a method for the in vitro or in vivo diagnosis of cardiovascular diseases, in particular high blood pressure, stenosis, vessel occlusion and/or other thrombotic events, wherein the nucleotide at position 950 of a nucleic acid coding for the human ARK2 protein or the amino acid at position 298 of the human ARK2 protein of a sample of a person is determined as well as to the use of ARK2 for the development and/or production of a medicament for treating a cardiovascular disease.
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Database DSNP (Online) ncbi; C050T SNP ARK2, Aug. 29, 2001, refSNP ID: RS2241909 XP002372732, retrieved from NCBI Database accession No. RS2241909, the whole document.
Database DBSNP (Online) ncbi; C950T SNP ARK2, Oct. 16, 2000. “refSNP ID: RS1059476” XP002372733, retrieved from NCBI Database accession No. RS2241909, the whole document.
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Herrmann Matthias
Kozian Detlef
Leeuw Thomas
Maerz Winfried
Renner Wilfried
Kapushoc Stephen
Pontenot J. Darrell
Sanofi-Aventis
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