Method for the determination of coagulation parameters

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor

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435 4, 435 725, 435 696, 435975, 435810, 436 16, 436 18, 436 63, 436 74, 514822, 514834, C12Q 156, C12Q 100, G01N 3353, G01N 3100

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055522963

ABSTRACT:
In a method for the determination of coagulation parameters in sample material via a reaction cascade in which a thrombin-catalyzed formation of a fibrin clot from fibrin monomers occurs and the formation of the fibrin clot is measured, an inhibitor of F XIII is added. By this means the reaction vessel can be used several times for coagulation tests.

REFERENCES:
patent: 4968494 (1990-11-01), Claremon et al.
patent: 5185149 (1993-02-01), Bladwin et al.
Nelson et al, Blood, vol. 52/3, pp. 581-591, (Abstract) 1978.

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