Method for the determination of antigens or antibodies in the pr

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic

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436507, 436509, 436825, 436962, G01N 33546, G01N 33564

Patent

active

054666112

ABSTRACT:
The invention relates to a latex agglutination method for the detection or determination of one partner of an antigen-antibody reaction, wherein, in order to suppress non-specific reactions, to, for example, Clq and rheumatoid factors the immunochemical reaction takes place in the presence of an immune complex which does not contain any antibody or antigen that is specific for one of the partners.

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patent: 4670381 (1987-06-01), Frickey et al.
patent: 5017473 (1991-05-01), Wagner
Masson et al. "Immunoassay by Purtizle Counting" in Manual of Clinical Laboratory Immunology 3rd Ed.
Rose et al eds. American Society for Microbiology, 1986 pp. 43-48.
Galvin et al. "Particle-Enhanced Immunoassays" in Manual of Clinical Laboratory Immunology 3rd Ed.
Rose et al eds, American Society for Microbiology 1986 pp. 38-42.
Ho et al: J. Clin. Microbiology 27(5) 952-958, 1989.
Price et al; Ann Clin Biochem 20: 1-14, 1983.
Foster et al; "Turbidimetry" In Manual of Clinical Laboratory Immunology, 3rd Ed, Rose et al Eds.; American Society for Microbiology Washington D.C., 1986 pp. 25-32.
Sternberg J. C.; "Rate Nephelometry" In Manual of Clinical Laboratory Immunology 3rd Ed, Rose et al Eds; American Society for Microbiology, Washington, D.C. 1986 pp. 33-37.
Kolb et al J. Clin. Chem. Clin. Biochem 24:379-386, 1986.
Interference By Rheumatoid Factor With The Detection of C-Reactive Protein By The Latex Agglutination Method, Deyo et al., The Journal Of Rheumatology 7(3):279-287 (1980).

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