Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1991-12-12
1994-05-31
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
427 2, 436506, 436518, G01N 33543, G01N 33564
Patent
active
053169158
ABSTRACT:
The invention relates to a method for the determination of antibodies against lipocortins (annexins) in a body fluid of a species, using proteins from the lipocortin family bound to a solid phase and using a labeled bioaffinity binding partner which is directed against single classes or a plurality of classes of immunoglobulins of this species.
REFERENCES:
patent: 4434227 (1984-02-01), Unger
"Presence of Autoantibody for Phospholipase Inhibitory Protein, Lipomodulin, in Patients with Rheumatic Diseases", for Proc. Natl. Acad. Sci. USA, by Fusao Hirata, et al., pp. 3190-3194, May 1981.
"Autoantibodies to Recombinant Lipocortin-1 in Rheumatoid Arthritis and Systemic Lupus Erythematosus", for Annals of the Rheumatic Diseases (1989), vol. 48, pp. 843-850, by N. J. Goulding et al.
"Purification and Characterization of Six Annexins from Human Placenta" for Biol. Chem. Hoppe-Seyler, vol. 371 pp. 383-388, May 1990, by Juergen Roemisch, et al.
"Annexin Proteins PP4 and PP4-X", for Biochem. J. (1990) vol. 272 pp. 223-229, by Juergen Roemisch, et al.
"Enzyme Immunoassays in Diagnostic Medicine", for Bull World Health Organ., vol. 53, 1976, pp. 55-65, by A. Voller, et al.
Harlow, Ed Antibodies: A Laboratory Manual Cold Spring Harbor, N.Y., 1988 pp. 553-577, 621-622.
Kraus Michael
Romisch Jurgen
Behringwerke Aktiengesellschaft
Saunders David
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