Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1987-12-17
1990-12-11
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 21, 435 28, 435810, 435947, 436501, 436518, 436529, 436530, 436531, 436544, 436808, 436828, G01N 33535, G01N 33543, G01N 33566, G01N 33569
Patent
active
049770799
ABSTRACT:
An immunoenzimatic method is disclosed for the detection and the measurement of anti-P. falciparum sporzoite antibodies in human blood and/or in its derivatives, which operates with a synthetic antigen-enzyme conjugate capable of forming with the antisporozoite antibodies a stable antibody-synthetic antigen-enzyme complex, and one or more proteins absorbed and/or covalently linked to a solid support, which eagerly bind the antisporozoite antibody of said complex.
The method, thanks to its simpleness, specificity and rapidity, is particularly useful in epidemiologic investigations into malaria and into the efficacy of an antimalarial vaccine.
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Bernardi Adriano
Nuzzolo Carlo A.
Pessi Antonello
Verdini Antonio S.
Eniricerche S.p.A.
Kepplinger Esther L.
Saunders David A.
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