Method for the detection of nitric oxide

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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436118, 436173, A61K 4900, G01N 3300

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active

053587030

ABSTRACT:
A method of detecting nitric oxide in an aqueous body fluid of a mammal comprises introducing into the body fluid the agents required to form a water-soluble, stable, paramagnetic complex with nitric oxide and then subjecting the body fluid to magnetic resonance methods which can detect the complex to determine if any nitric oxide was present. A paramagnetic complex containing nitric oxide also is described, as well as, a method of diagnosing septic shock in a mammal by stabilizing and detecting the presence of nitric oxide in a body fluid of the mammal.

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