Method for the detection of microsatellite instability for tumor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 536 2433, C12Q 168, C12P 1934, C07H 2104

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06150100&

ABSTRACT:
The invention concerns a method for the determination of the genomic instability at 5 selected microsatellite loci. The analysis of these selected loci is suitable for making prognostic tumour diagnoses, for analysing hereditary tumor predisposition as well as for early tumor detection. This method is of particular importance for the diagnosis of tumors of the gastrointestinal tract such as colorectal tumors.

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