Method for the detection of metabolically labelled DNA

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 71, 435 721, 435 75, 435 794, 435 18, 435 19, 4351737, 436518, 436528, 436531, 436538, 935 77, C12Q 168, G01N 3353, G01N 33537, G01N 33543

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057006393

ABSTRACT:
The invention concerns a method for the non-radioactive detection of metabolically labelled DNA, in one aspect detecting labelled DNA indicative of cell lysis or apoptosis.

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Monosov et al., 1992. Immunoelectron microscopy of deoxyribonucleic acid in procaryotic cells. Acta Histochem. Cytochem. 25: 137-141.
Hutchison et al., 1982. In situ hybridization at the electron microscope level: hybrid detection by autoradiography and colloidal gold. Journal of Cell Biology 95: 609-618.
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Martinon et al., 1987. In vitro proliferation of human lymphjocytes measured by an enzyme immunoassay using an anti-5-bromo-2-deoxyuridine monoclonal antibody. J. Clin. Lab. Immunol. 23: 153-159.
Death and the cell; Duvall et al. Immunology Today 7(4) 115-119 (1986).

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