Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic
Reexamination Certificate
2008-07-08
2008-07-08
Le, Long V. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is organic
C436S544000, C436S125000, C436S161000, C435S007100, C423S325000, C530S402000, C530S406000
Reexamination Certificate
active
07396691
ABSTRACT:
The present invention relates to a method for detecting and/or measuring the concentration of fluoride (F−) or hydrogen fluoride (HF) in a sample, comprising the steps consisting of bringing said sample, in aqueous solution, into contact with a silylated organic compound in order to obtain a measurement solution, with said silylated organic compound being desilylated when it is in the presence of hydrofluoric acid or a fluoride, with the silylated organic compound and the desilylated organic compound being able to be detected and/or measured separately from each other; and detecting and/or measuring, in said measurement solution, the appearance of the desilylated against compound or the disappearance of the silylated organic compound, which takes place if fluoride or hydrogen fluoride is present in the sample. The method enables the presence of hydrogen fluoride or of fluorine to be detected very easily and expediently at concentrations of 10−2l of HF/106l of air (10 ppb) or else of 0.5 to 1 μg/ml of HF in solution. The kit of the present invention comprises the components which are required for implementing this method. The method of the invention makes it possible to detect fluorine at concentrations of the order of 0.001 μg/ml.
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I
Ezan Eric
Pradelles Philippe
Sagot Marie-Astrid
Commissariat a l''Energie Atomique
Haq Shafiqul
Le Long V.
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
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