Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1985-10-21
1989-02-21
Rosen, Sam
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
4351721, 4351722, 436518, 436527, 436528, 436529, 436531, 436536, 436542, 436543, 436548, G01N 3353, G01N 33543
Patent
active
048064670
ABSTRACT:
The present invention relates to a method of detecting either antibody or antigen in the serum of horses infected with equine infectious anemia using a competitive enzyme-linked immunoabsorbent assay technique and reagents useful in such an assay. The competitive enzyme-linked immunoabsorbent assay incorporates a purified virus antigen conjugate and a monoclonal antibody specific for the virus antigen as both the reacting and competing components. Alternatively, the competitive enzyme-linked immunoabsorbent assay incorporates a purified virus antigen and a monoclonal antibody conjugate specific for the viral antigen as both reacting and competing components. This invention also relates to detecting antigen and antibody found in other retrovirus infections such as Acquired Immunodeficiency Syndrome in humans.
REFERENCES:
Chem. Abst. 10th Collect. Index, vol. 86-95 (1977-1981) General Subjects, pp. 24549GS and 24588GS-24589GS.
Maggio-Enzyme-Immunoassay (1980), CRC Press, pp. 106-107.
Matsushita et al.-Am. Assn. Vet. Lab. Diag. 27th Annual Proceed. (1984) pp. 27-34.
Hesterberg Lyndal K.
Matsushita Tatsuo
Porter James P.
Fermenta Animal Health Company
Rosen Sam
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