Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving hydrolase
Reexamination Certificate
2006-05-12
2008-09-16
Gitomer, Ralph (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving hydrolase
C435S024000, C435S004000
Reexamination Certificate
active
07425425
ABSTRACT:
A method involves the detection of enzyme-catalyzed cleavage reactions using modular chemical compounds as substrates for the enzymes involved, and detection is effected by use of molecular-weight-sensitive methods.
REFERENCES:
patent: 6342611 (2002-01-01), Weber et al.
patent: 2001/0046668 (2001-11-01), Levine et al.
patent: 2 791 141 (1999-03-01), None
patent: WO 00/52199 (2000-09-01), None
patent: WO 00/72016 (2000-11-01), None
Bergmann, F. and Bannwarth, W., “Solid Phase Synthesis of Directly Linked Peptide-Oligodeoxnucleotide Hybrids Using Standard Synthesis Protocols”, Tetrathedron Letters, 36:11 (1995), 1839-42.
Levine et al., “Measurement of Specific Protease Activity Utilizing Fluorescence Polarization”, Analytical Biochemistry, 247 (1997), 83-88.
Robles, J., “Synthesis and Enzymatic Stability of Phosphodiester-Linked Peptide-Oligonucleotide Hybrids”, Bioconjugate Chem., 8 (1997), 785-88.
Robles, J. et al., “Towards Nucleopeptides Containing Any Trifunctional Amino Acid”, Tetrahedron, 55 (1999), 13251-64.
Singh et al., “Fluorescence Polarization for Monitoring Ribozyme Reactions in Real Time”, Biotechniques, 29 (2000), 344-51.
Fries Joachim
Jungmann Joern
Lopez-Calle Eloisa
Evotec Oai AG
Gitomer Ralph
Jacobson & Holman PLLC
LandOfFree
Method for the detection of enzyme-catalyzed cleavage... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for the detection of enzyme-catalyzed cleavage..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the detection of enzyme-catalyzed cleavage... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3987569