Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-03-03
2011-10-04
Szperka, Michael (Department: 1644)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007920, C435S007930, C435S007940, C435S007950, C530S853000, C530S868000, C514S009800
Reexamination Certificate
active
08030007
ABSTRACT:
A method for diagnosing endometriosis in a human subject comprising the steps of detecting a test amount of an antibody that specifically binds to SEQ ID NO: 6 polypeptide or a truncated peptide comprising an epitope of SEQ ID NO: 6 in a sample from the subject; and comparing the test amount with a normal range of the antibody in a control sample from a subject who does not suffer from endometriosis, whereby a test amount above the normal range provides a positive indication in the diagnosis of endometriosis.
REFERENCES:
patent: 4489166 (1984-12-01), Joshi
patent: 5618680 (1997-04-01), Miron et al.
patent: 5843673 (1998-12-01), Sharpe-Timms
patent: 5877284 (1999-03-01), Lyttle
patent: 6165767 (2000-12-01), Lal et al.
patent: 6294662 (2001-09-01), Tabibzadeh
patent: 6376201 (2002-04-01), Miron et al.
patent: 6387629 (2002-05-01), Schneider et al.
patent: 6525187 (2003-02-01), El Shami et al.
patent: 6531277 (2003-03-01), Timms
patent: 6540980 (2003-04-01), Blumenthal et al.
patent: 6645725 (2003-11-01), Yeaman
patent: 6777182 (2004-08-01), Baban et al.
patent: 6780594 (2004-08-01), Hess-Stumpp et al.
patent: 7049069 (2006-05-01), Chegini et al.
patent: 7122322 (2006-10-01), Timms
patent: 2001/0044158 (2001-11-01), Yeaman
patent: 2002/0192647 (2002-12-01), Smith
patent: 2007/0184444 (2007-08-01), Abbas et al.
patent: 2007/0224201 (2007-09-01), Wu et al.
patent: 100 48 633 (2002-04-01), None
patent: 0 387 027 (1990-12-01), None
patent: 1 130 123 (2001-09-01), None
patent: 1 191 107 (2002-03-01), None
patent: 92/16535 (1992-10-01), None
patent: 94/28021 (1994-12-01), None
patent: 97/35016 (1997-09-01), None
patent: 99/04265 (1999-01-01), None
patent: 99/49037 (1999-09-01), None
patent: 99/63116 (1999-12-01), None
patent: 00/43789 (2000-07-01), None
patent: 00/63675 (2000-10-01), None
patent: 00/75321 (2000-12-01), None
patent: 01/32920 (2001-05-01), None
patent: 02/068579 (2002-09-01), None
patent: 2004/030615 (2004-04-01), None
patent: 2004/087874 (2004-10-01), None
Ballinger, et al., “Identification of CHIP: a Novel Tetratricopeptide Repeat-Containing Protein That Interacts with Heat Shock Proteins and Negatively Regulates Chaperone Functions”, Mol. Cell Biol., 19:4535-4545 (1999).
Brosens, et al., “Is laparoscopy the gold standard for the diagnosis of endometriosis?”, Eur. J. Obstet. Gynecol. Repro. Biol., 88:117-119 (2000).
Brosens, et al., “Noninvasive diagnosis of endometriosis: the role of imaging and markers”, Obstet. Gynecol. Clin. North Am., 30(1):95-114 (2003).
Canavan, et al., “Managing edometriosis: Strategies to minimize pain and damage”, Postgrad. Med., 107(3):213-224 (2000).
Coxhead, et al., “Familial inheritance of endometriosis in a British population. A case control study”, J. Obstet. Gyn., 13:42-44 (1993).
Galfre, et al., “Antibodies to major histocompatibility antigens produced by hybrid cell lines”, Nature, 266:550-552 (1977).
Gosselin, et al., “Insights into the physiopathology of endometriosis—novel diagnostic and therapeutic approaches”, Curr. Opin. Endo. & Metabol. Invest. Drugs, 1(1):31-43 (1999).
Husby, et al., “Diagnostic delay in women with pain and endometriosis”, Acta Obstet. Gynecol Scand., 82:649-653 (2003).
Koninckx, “Is mild endometriosis a disease? Is mild endometriosis a condition occurring intermittently in all women?”, Hum. Reprod., 9(12):2202-2211 (1994).
Mahnke, et al., “Vascular endothelial growth factor and interleukin-6 in peritoneal fluid of women with endometriosis”. Fertil. Steril., 73(1): 166-170 (2000).
Matalliotakis, et al., “A Randomized Comparison of Danazol and Leuprolide Acetate Suppression of Serum-Soluble CD23 Levels in Endometriosis”, Obstet. Gynecol., 95:810-813 (2000).
Mol, et al., “The performance of CA-125 measurement in the detection of endometriosis: a meta-analysis”, Fertil. Steril., 70(6):1101-1108 (1998).
Oi, et al., “Immunoglobin-Producing Hybrid Cell Lines”, in B.B. Mishell, et al. (eds), “Selected Methods in Cellular Immunology”, W.H. Freeman, San Francisco, CA, pp. 351-372 (1980).
Pillai, et al., “Antibodies to Endometrial Transferrin and Alpha 2-Heremans Schmidt (HS) Glycoprotein in Patients with Endometriosis”, Am. J. Reprod. Immunol., 35:483-494 (1996).
Pillai, et al., “Effects of Antibodies to Transferrin and Alpha 2-HS Glycoprotein on in Vitro Sperm Motion: Implications in Infertility Associated with Endometriosis”, Am. J. Reprod. Immunol., 39:235-242 (1998).
Redwine., “Was Sampson wrong?”, Fertil. Steril., 78(4):686-693 (2002).
Scanlan, et al., “Characterization Of Human Colon Cancer Antigens Recognized By Autologous Antibodies”, Int. J. Cancer. 76:652-658 (1996).
Sharkey, et al., “Vascular Endothelial Growth Factor Expression in Human Endometrium is Regulated by Hypoxia”, J. Clin. Endocrinol. Metab., 85(1):402-409 (2000).
Sharpe-Timms. et al., “Endometriotic Lesions Synthesize and Secrete a Haptoglobin-Like Protein”, Biol. Reprod., 58:986-994 (1998).
Shulman, et al., “A better cell line for making hybridomas secreting specific antibodies”, Nature, 276:269-270 (1978).
Thomas, et al., “Evidence that Endometriosis Behaves in a Malignant Manner”, Gynecol. Obstet. Invest., 50(supp. 1) 2-10 (2000).
Van Voorhis, et al., “Autoantibodies and infertility: a review of the literature”, J. Reprod. Immunol., 33:239-256 (1997).
Vigano, et al., “Endometrial Release of Soluble Intercellular Adhesion Molecule 1 and Endometriosis: Relationship to the Extent of the Disease”. Obstet. Gynecol., 95(1):115-118 (2000).
Wolin, et al., “The Ro 60 kDa autoantigen comes into focus: Interpreting epitope mapping experiments on the basis of structure”, Autoimmunity Reviews, 5:367-372 (2006).
Colman, “Effects of amino acid sequence changes on antibody-antigen interations”, Research in Immunol., 145:33-36 (1994).
Harlow, et al., “Using Antibodies: A Laboratory Manual”, Cold Spring Harbor Laboratory Press. Cold Spring Harbor, New York, pp. 75-76 (1999).
OM protein, protein search using sw model. Run May 31, 2006, 03:23-21. pp. 1-3.
Accession No. BC007545.1 (GI No. 14043118, first seen in NCBI May 15, 2001 4:50 pm).
Accession No. AF129086.1 (GI No. 4928063, first seen at NCBI Jun. 10, 1999 12:07 am).
Accession No. NM—005861.2 (GI No. 56181386, first seen at NCBI Jun. 10, 1999 9:01 am).
Accession No. AF432221.1 (GI No. 19851935, first seen at NCBI Apr. 1, 2002 12:19 am).
Accession No. AAK61242.1 (GI No. 14336710, first seen at NCBI Jun. 11, 2001 3:07 pm).
Accession No. AAD33400.1 (GI No. 4928064, first seen at NCBI Jun. 1, 1999 12:07 am).
Accession No. AAC18038.1 (GI No. 3170178, first seen at NCBI Jun. 2, 1998 12:21 am).
Campbell Bruce
El Shami A. Said
Sahakian Niver
Sustarsic Dennis
Siemens Healthcare Diagnostics Inc.
Stein Kevin
Szperka Michael
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