Method for the detection of antibodies

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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23230B, 422 57, G01N 3316, G01N 3106

Patent

active

041691385

ABSTRACT:
A method for the detection of antibodies immunochemically bound to the corresponding antigen fixed to a smooth surface of glass, metal, polymerfilm or the like. The surface with antigen bound antibodies is contacted with a suspension of small water-insoluble particles to which a biopolymer is directly bound, said biopolymer having the ability of binding to said antibodies, preferably at a non-antigen binding structure of the antibodies. The particles are then adsorbed only on that part of the surface where antibodies are specifically bound and the adsorbed particles forms a coating that is clearly visible by the eye.

REFERENCES:
patent: 3789116 (1974-01-01), Kay
patent: 3904367 (1975-09-01), Golibersuch
patent: 3966898 (1976-06-01), Sjoquist
patent: 4054646 (1977-10-01), Giaever
patent: 4061466 (1977-12-01), Sjoholm
patent: 4066744 (1978-01-01), Price
S. Jonsson et al., Europ. Jour. of Immunology, 4, 29-33, Jan. 1974.
H. Hjelm et al., FEBS Letters, 28, 73-76, Nov. 1972.

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