Method for the detection of anencephaly

Details Method for the detection of anencephaly Method for the detection of anencephaly

1995-03-16

1999-03-23

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 231, 536 2433, 536 243, 800 2, C12Q 168, C12P 1934, C07H 2102, C07H 2104

Patent

active

058857729

ABSTRACT:
The invention includes methods and materials, including probes, to be used as diagnostic tools for detecting anencephaly. Such methods may be practiced by both manual and automated means, and in the instance of the latter, suitable equipment for such automated performance is also contemplated. Also included within the invention are mouse embryos null for a gene encoding a protein kinase C substrate which binds calcium-calmodulin and regulates cell movement and membrane traffic, and cells derived from such embryos.

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