Method for the control of antibiotic-resistant gram positive bac

Details Method for the control of antibiotic-resistant gram positive bac Method for the control of antibiotic-resistant gram positive bac

1996-06-21

1999-02-02

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514 13, A61K 3816

Patent

active

058665390

ABSTRACT:
The invention concerns methods for killing antibiotic-resistant pathogenic bacteria responsible for disease in humans and animals. The methods employ a lanthocin such as nisin as bactericidal agent.

REFERENCES:
patent: 4931390 (1990-06-01), Recsei
patent: 4980163 (1990-12-01), Blackburn et al.
patent: 5217950 (1993-06-01), Blackburn et al.
patent: 5260271 (1993-11-01), Blackburn et al.
patent: 5334582 (1994-08-01), Blackburn et al.
patent: 5512269 (1996-04-01), Molinay Vedia et al.
Brotz et al. "Mode of Action of the Lantibiotic Mersacidin: Inhibition of Peptidoglycan Biosynthesis . . . " Antimicrob. Agents Chemotherapy. 39 (3): 714-719, 1995. (abstract only).
Barrett et al. "In Vitro Activity of Mersacidin (M87-1551), . . . " Diagn. Microbiol. Infect. Dis. 15(7): 641-644, 1992. (abstract only).
Murray, B.E. "The Life and Times of Enterococcus" Clin. Microbiol. Rev. 3(1): 46-65, 1990. (abstract only).
"Invasive Group A Streptococcal Infections--United Kingdom, 1994" MMWR, pp. 401-402, 1994.
Bavin et al. "Nisin in Experimental Tuberculosis." Lancet 1:127-129, 1952.
Gowans et al. "Some Properties of Nisin." Brit. J. Pharmacol. 7:438-449, 1952.
Chatterjee et al. "Mersacidin, a New Antibiotic From Bacillus. In vitro and in vivo antibacterial activity." J. Antibiot. (Japan), 45(6):839-845, 1992. (abstract only).
Szybalski, W. "Genetic Studies in Microbial Cross Resistance to Toxic Agents," Dept. Health and Human Services, FDA Fed. Regis. 53(66):pp. 1095-1103, 1988. (odd-numbered pages only).
Hirsch et al. "Some Recent Applications of Nisin." Lancet, ii:190-193, 1949.
Mattick et al. "Further Observations on an Inhibitory Substance (nisin) from Lactic Streptococci" Lancet 2:5-8, 1947.
Somma et al. "Gardimycin, a New Antibiotic Inhibiting Peptidoglycan Synthesis" Antimicrob. Ag. Chemother. 11:396-401, 1997.
Arioli et al. "Gardimycin, a New Antibiotic from Actinoplanes" J. Antibiot. 29:511-515, 1976.
Karchmer, A.W. "Staphylococcus Aureus and Vancomycin: The Sequel" Ann. Int. Med. 115(9):739-741, 1991.
Jung et al. "Nisin and Novel Lanibiotics" ESCOM Science Publishers, Leiden, pp. 1-34, 1991.
Emori et al. "An Overview of Nosocomial Infections, . . . " Clin. Microbiol. Rev. 6(4):428-442, 1993.
Ramseier, H.R. "Die Wirkung von nisin auf closridium butyricum Prazm." Archiv. fur Mikrobiol. 37:57-94, 1960.
Hossack et al. "The Effects of Nisin on the Sensitivity of a Range of Microorganisms to Antibiotics. . . " Federal Register, vol. 53, No. 668, pp. 1-30, Apr. 6, 1988.
Stutman, H.R. "Penicillin-resistant Streptococcus Pneumoniae. . . " Infections in Medicine 10: Suppl. D.:51-55, 1993.
Thornsberry et al. "Increasing Penicillin Resistance in Streptococcus Pneumoniae in the U.S. . . . " Infections in Medicine 10 Suppl. D.:15-24, 1993.
Reisinger et al. "The Effect of Nisin on Murein Synthesis" Arch. Microbiol. 127:187-193, 1980.
Nobel et al. "Co-transfer of Vancomycin and Other Resistance Genes . . . " FEMS Microbiol. Lett. 93:195-198, 1992.
Sahl, H. -G., et al., Eur. J. Biochem. 230,827-853 (1995).
Jung, G., Lantibiotics: A Survey, In: Nisin and Novel Lantibiotics, Jung, G. and Sahl, H. -G., eds., ESCOM Science Publishers, Leiden, pp. 1-34 (1991).
Szybalski, W., Antibiotics and Chemotherapy 3, 1095-1103 (1953).
Goldstein, B.P., "Tuberculosis in the 1990s," La Chimica e l'Industria 76, 196-198 (1994).
Cole, S.T. Trends in Microbiology 2, 411-415 (1994).
Orberg et al. Survey of Antimicrobial Resistance in Lactic Streptococci. Applied and Environmental Microbiology, Mar. 1985, vol. 49, No. 3, pp. 538-542.

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