Method for the commercial production of helminths antigens

Details Method for the commercial production of helminths antigens Method for the commercial production of helminths antigens

1985-06-12

1988-07-12

Kight, John

Drug, bio-affecting and body treating compositions

Lymphokine

424 95, A61K 3900

Patent

active

047569085

ABSTRACT:
An easily cultured worm is genetically modified such that its surface antigens on its modified form are immunologically identical to the surface antigens of a parasitic worm. Specifically, C. elegans is genetically modified to produce antigens corresponding to the antigens of D. immitis which causes heartworm infection. The antigens derived from the easily cultured worm are used to form a vaccine and/or diagnostic.

REFERENCES:
patent: 3511908 (1970-05-01), Brock et al.
patent: 3674860 (1972-07-01), Welter et al.
patent: 4345026 (1982-08-01), Lew
patent: 4396600 (1983-08-01), Messineo et al.
Edgar et al., Science, vol. 198, pp. 1285-1286 (1977).

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