Method for the chemical separation of GE-68 from its...

Details Method for the chemical separation of GE-68 from its... Method for the chemical separation of GE-68 from its...

2008-05-08

2010-06-01

Berman, Jack I (Department: 2881)

Radiant energy

Fluent material containment, support or transfer means

With irradiating source or radiating fluent material

C423S002000, C252S625000, C252S645000

Reexamination Certificate

active

07728310

ABSTRACT:
The present invention is directed to a generator apparatus for separating a daughter gallium-68 radioisotope substantially free of impurities from a parent gernanium-68 radioisotope, including a first resin-containing column containing parent gernanium-68 radioisotope and daughter gallium-68 radioisotope, a source of first eluent connected to said first resin-containing column for separating daughter gallium-68 radioisotope from the first resin-containing column, said first eluent including citrate whereby the separated gallium is in the form of gallium citrate, a mixing space connected to said first resin-containing column for admixing a source of hydrochloric acid with said separated gallium citrate whereby gallium citrate is converted to gallium tetrachloride, a second resin-containing column for retention of gallium-68 tetrachloride, and, a source of second eluent connected to said second resin-containing column for eluting the daughter gallium-68 radioisotope from said second resin-containing column.

REFERENCES:
patent: 6157036 (2000-12-01), Whiting et al.
patent: 2003/0129366 (2003-07-01), Lawrence et al.
patent: 2006/0022127 (2006-02-01), Zyuzin

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