Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process...
Patent
1985-11-12
1990-06-19
Nucker, Christine M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
435 3, 435111, 435114, 435813, 435818, 435819, C12P 100, C12P 1904, C17P 1906, C12Q 300
Patent
active
049353489
ABSTRACT:
To improve the yield and/or reduce the energy cost in carrying out a microbiological or enzymatic process in a reactor and to make the reaction conditions essentially independent of the size of the reactor, it is proposed to make use, as a reactor, of an endless circulation tube in which the reaction components are circulated essentially according to a plug flow and in this process are fed through one or more in-line mixers fitted inside the tube. This method and reactor are suitable in particular for the preparation by fermentation of polysaccharides, especially xanthan, in which water, a production medium containing one or more sugars and nutrient salts and an inoculating material of a suitable aerobic bacterium are introduced into the said reactor tube and exposed to fermentation with air being supplied. Preferably the concentration of a reaction component or a value derived therefrom is measured at at least one point and the reaction velocity is regulated on the basis of the said measurement within critical limits.
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Gerard oosterhuis Nicholaas M.
Koerts Kees
Beisner William H.
Cooperatieve Vereniging Suiker Unie U.A.
Nucker Christine M.
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