Method for the biological preparation of hydroxyvitamin D compou

Details Method for the biological preparation of hydroxyvitamin D compou Method for the biological preparation of hydroxyvitamin D compou

1991-06-07

1995-12-12

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing at least three carbocyclic rings

435101, C12P 702

Patent

active

054749239

ABSTRACT:
A method for introducing hydroxyl groups into vitamin D compound at the 1.alpha.- and/or 25-positions in the presence of a cyclodextrin compound by the use of a reaction mixture containing a microorganism being capable of hydroxylating vitamin D compound or a enzyme produced from the microorganism, is disclosed.

REFERENCES:
patent: 4892821 (1990-01-01), Omura et al.
Bogoslovskii et al., Proc. Workshop Vitamin D, 7th, 1988 pp. 1021-1023.
Takeda et al., J. Feron, and Bioeng., vol. 78, pp. 380-382, 1994.
Sawada et al, Appl. Microbiol. Biotechnol., 1990, vol. 32, pp. 556-559.

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