Method for the asymmetric hydrogenation of .alpha.-ketocarbonyl

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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560179, C07D30726

Patent

active

051772205

ABSTRACT:
Asymmetric hydrogenation of .alpha.-ketocarbonyl compounds, especially .alpha.-ketolactones, to the corresponding, optically active .alpha.-hydroxycarbonyl compounds in the presence of iridium diphosphine complexes as catalyst and dicarboxylic acid imides as co-catalyst.

REFERENCES:
patent: 4343741 (1982-08-01), Townsend et al.
patent: 4634775 (1987-01-01), Beck et al.
patent: 4652657 (1987-03-01), Broger et al.
patent: 4668795 (1987-05-01), Andrade et al.

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